2017-2019

Khader, S. A., Divangahi, M., Hanekom, W., Hill, P. C., Maeurer, M., Makar, K. W., Mayer-Barber, K. D., Mhlanga, M. M., Nemes, E., Schlesinger, L. S., van Crevel, R., Vankayalapati, R., Xavier, R. J., Netea, M. G., & Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18 (2019). Targeting innate immunity for tuberculosis vaccination. The Journal of clinical investigation, 129(9), 3482–3491. https://doi.org/10.1172/JCI128877

Walk, J., de Bree, L. C. J., Graumans, W., Stoter, R., van Gemert, G. J., van de Vegte-Bolmer, M., Teelen, K., Hermsen, C. C., Arts, R. J. W., Behet, M. C., Keramati, F., Moorlag, S. J. C. F. M., Yang, A. S. P., van Crevel, R., Aaby, P., de Mast, Q., van der Ven, A. J. A. M., Stabell Benn, C., Netea, M. G., & Sauerwein, R. W. (2019). Outcomes of controlled human malaria infection after BCG vaccination. Nature communications, 10(1), 874. https://doi.org/10.1038/s41467-019-08659-3

Domínguez-Andrés, J., Novakovic, B., Li, Y., Scicluna, B. P., Gresnigt, M. S., Arts, R. J. W., Oosting, M., Moorlag, S. J. C. F. M., Groh, L. A., Zwaag, J., Koch, R. M., Ter Horst, R., Joosten, L. A. B., Wijmenga, C., Michelucci, A., van der Poll, T., Kox, M., Pickkers, P., Kumar, V., Stunnenberg, H., … Netea, M. G. (2019). The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity. Cell metabolism, 29(1), 211–220.e5. https://doi.org/10.1016/j.cmet.2018.09.003

Freyne, B., Donath, S., Germano, S., Gardiner, K., Casalaz, D., Robins-Browne, R. M., Amenyogbe, N., Messina, N. L., Netea, M. G., Flanagan, K. L., Kollmann, T., & Curtis, N. (2018). Neonatal BCG Vaccination Influences Cytokine Responses to Toll-like Receptor Ligands and Heterologous Antigens. The Journal of infectious diseases, 217(11), 1798–1808. https://doi.org/10.1093/infdis/jiy069

Arts, R. J. W., Moorlag, S. J. C. F. M., Novakovic, B., Li, Y., Wang, S. Y., Oosting, M., Kumar, V., Xavier, R. J., Wijmenga, C., Joosten, L. A. B., Reusken, C. B. E. M., Benn, C. S., Aaby, P., Koopmans, M. P., Stunnenberg, H. G., van Crevel, R., & Netea, M. G. (2018). BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell host & microbe, 23(1), 89–100.e5. https://doi.org/10.1016/j.chom.2017.12.010

Bekkering, S., Arts, R. J. W., Novakovic, B., Kourtzelis, I., van der Heijden, C. D. C. C., Li, Y., Popa, C. D., Ter Horst, R., van Tuijl, J., Netea-Maier, R. T., van de Veerdonk, F. L., Chavakis, T., Joosten, L. A. B., van der Meer, J. W. M., Stunnenberg, H., Riksen, N. P., & Netea, M. G. (2018). Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell, 172(1-2), 135–146.e9. https://doi.org/10.1016/j.cell.2017.11.025

Mitroulis, I., Ruppova, K., Wang, B., Chen, L. S., Grzybek, M., Grinenko, T., Eugster, A., Troullinaki, M., Palladini, A., Kourtzelis, I., Chatzigeorgiou, A., Schlitzer, A., Beyer, M., Joosten, L. A. B., Isermann, B., Lesche, M., Petzold, A., Simons, K., Henry, I., Dahl, A., … Chavakis, T. (2018). Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell, 172(1-2), 147–161.e12. https://doi.org/10.1016/j.cell.2017.11.034

Christ, A., Günther, P., Lauterbach, M. A. R., Duewell, P., Biswas, D., Pelka, K., Scholz, C. J., Oosting, M., Haendler, K., Baßler, K., Klee, K., Schulte-Schrepping, J., Ulas, T., Moorlag, S. J. C. F. M., Kumar, V., Park, M. H., Joosten, L. A. B., Groh, L. A., Riksen, N. P., Espevik, T., … Latz, E. (2018). Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell, 172(1-2), 162–175.e14. https://doi.org/10.1016/j.cell.2017.12.013

Kaufmann, E., Sanz, J., Dunn, J. L., Khan, N., Mendonça, L. E., Pacis, A., Tzelepis, F., Pernet, E., Dumaine, A., Grenier, J. C., Mailhot-Léonard, F., Ahmed, E., Belle, J., Besla, R., Mazer, B., King, I. L., Nijnik, A., Robbins, C. S., Barreiro, L. B., & Divangahi, M. (2018). BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell, 172(1-2), 176–190.e19. https://doi.org/10.1016/j.cell.2017.12.031