2020-2022

Bannister, S., Kim, B., Domínguez-Andrés, J., Kilic, G., Ansell, B. R. E., Neeland, M. R., Moorlag, S. J. C. F. M., Matzaraki, V., Vlahos, A., Shepherd, R., Germano, S., Bahlo, M., Messina, N. L., Saffery, R., Netea, M. G., Curtis, N., & Novakovic, B. (2022). Neonatal BCG vaccination is associated with a long-term DNA methylation signature in circulating monocytes. Science advances, 8(31), eabn4002. https://doi.org/10.1126/sciadv.abn4002

Kaufmann, E., Khan, N., Tran, K. A., Ulndreaj, A., Pernet, E., Fontes, G., Lupien, A., Desmeules, P., McIntosh, F., Abow, A., Moorlag, S. J. C. F. M., Debisarun, P., Mossman, K., Banerjee, A., Karo-Atar, D., Sadeghi, M., Mubareka, S., Vinh, D. C., King, I. L., Robbins, C. S., … Divangahi, M. (2022). BCG vaccination provides protection against IAV but not SARS-CoV-2. Cell reports, 38(10), 110502. https://doi.org/10.1016/j.celrep.2022.110502

Kong, L., Moorlag, S. J. C. F. M., Lefkovith, A., Li, B., Matzaraki, V., van Emst, L., Kang, H. A., Latorre, I., Jaeger, M., Joosten, L. A. B., Netea, M. G., & Xavier, R. J. (2021). Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes. Cell reports, 37(7), 110028. https://doi.org/10.1016/j.celrep.2021.110028

Divangahi, M., Aaby, P., Khader, S. A., Barreiro, L. B., Bekkering, S., Chavakis, T., van Crevel, R., Curtis, N., DiNardo, A. R., Dominguez-Andres, J., Duivenvoorden, R., Fanucchi, S., Fayad, Z., Fuchs, E., Hamon, M., Jeffrey, K. L., Khan, N., Joosten, L. A. B., Kaufmann, E., Latz, E., … Netea, M. G. (2021). Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nature immunology, 22(1), 2–6. https://doi.org/10.1038/s41590-020-00845-6

de Bree, L. C. J., Mourits, V. P., Koeken, V. A., Moorlag, S. J., Janssen, R., Folkman, L., Barreca, D., Krausgruber, T., Fife-Gernedl, V., Novakovic, B., Arts, R. J., Dijkstra, H., Lemmers, H., Bock, C., Joosten, L. A., van Crevel, R., Benn, C. S., & Netea, M. G. (2020). Circadian rhythm influences induction of trained immunity by BCG vaccination. The Journal of clinical investigation, 130(10), 5603–5617. https://doi.org/10.1172/JCI133934

Koeken, V. A., de Bree, L. C. J., Mourits, V. P., Moorlag, S. J., Walk, J., Cirovic, B., Arts, R. J., Jaeger, M., Dijkstra, H., Lemmers, H., Joosten, L. A., Benn, C. S., van Crevel, R., & Netea, M. G. (2020). BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner. The Journal of clinical investigation, 130(10), 5591–5602. https://doi.org/10.1172/JCI133935

Kalafati, L., Kourtzelis, I., Schulte-Schrepping, J., Li, X., Hatzioannou, A., Grinenko, T., Hagag, E., Sinha, A., Has, C., Dietz, S., de Jesus Domingues, A. M., Nati, M., Sormendi, S., Neuwirth, A., Chatzigeorgiou, A., Ziogas, A., Lesche, M., Dahl, A., Henry, I., Subramanian, P., … Chavakis, T. (2020). Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell, 183(3), 771–785.e12. https://doi.org/10.1016/j.cell.2020.09.058

Cirovic, B., de Bree, L. C. J., Groh, L., Blok, B. A., Chan, J., van der Velden, W. J. F. M., Bremmers, M. E. J., van Crevel, R., Händler, K., Picelli, S., Schulte-Schrepping, J., Klee, K., Oosting, M., Koeken, V. A. C. M., van Ingen, J., Li, Y., Benn, C. S., Schultze, J. L., Joosten, L. A. B., Curtis, N., … Schlitzer, A. (2020). BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment. Cell host & microbe, 28(2), 322–334.e5. https://doi.org/10.1016/j.chom.2020.05.014